diff --git i/dist/matlab/engine/__init__.py w/dist/matlab/engine/__init__.py
index 45bf9ae..d606284 100644
--- i/dist/matlab/engine/__init__.py
+++ w/dist/matlab/engine/__init__.py
@@ -50,10 +50,13 @@ except Exception as firstE:
 
 if firstExceptionMessage:
     try:
-        _arch_file = open(_arch_filename,'r')
-        _lines = _arch_file.readlines()
-        [_arch, _bin_dir,_engine_dir, _extern_bin_dir] = [x.rstrip() for x in _lines if x.rstrip() != ""]
-        _arch_file.close()
+        # TODO: Support for other architectures?
+        _arch = "glnxa64"
+        nix_install_location = os.path.expandvars('$MATLAB_INSTALL_DIR')
+        _bin_dir = os.path.join(nix_install_location, 'bin')
+        _engine_dir = os.path.join(nix_install_location,
+                'extern', 'engines', 'python', 'dist', 'matlab', 'engine', _arch)
+        _extern_bin_dir = os.path.join(nix_install_location, 'extern', 'bin', _arch)
         sys.path.insert(0,_engine_dir)
         sys.path.insert(0,_extern_bin_dir)
 
diff --git i/setup.py w/setup.py
index 49149e5..9f45560 100644
--- i/setup.py
+++ w/setup.py
@@ -72,7 +72,6 @@ class BuildEngine(build_py):
     def run(self):
         build_py.run(self)
         _target_dir = os.path.join(self.build_lib, _matlab_package, _engine_package)
-        self._generate_arch_file(_target_dir)
 
 
 if __name__ == '__main__':